Saturday, 21 April 2012

START A SOFT GELATIN CAPSULES MAKING BUSINESS


     

(311). START A SOFT GELATIN CAPSULES MAKING BUSINESS

Soft gelatin capsules consist of a filling, containing the dissolved or suspected active substance, and of a one-piece shell. Owing to the hermetic seal, the filling ingredients are protected against any harmful influence of the environment. Physical properties of solutions and suspensions, especially their homogeneity, allow the precision of dosage of active ingredients, rare in dry, orally received medications. In comparison with tablets and hard capsules, soft capsules require much less auxiliary substances, most of which are of herbal origin. The possibility to adjust the shell ingredients enables the adaptation of its parameters to specify requirements of storage conditions and especially to chemical as well as pharmacological properties of a medication.
The research on bioavailability of various medication forms has reportedly proved that the parameters of absorption and bioavailability of medications in the form of soft gelatine capsules are much better. It is mainly the result of one of the basic soft capsule features - the exact dispersion of a therapeutic substance in a liquid or semisolid medium. Owing to that, absorption of a medicament starts already at the moment of capsule disintegration in the alimentary tract, and is more effective thanks to the small size of suspended or dissolved particles of a medicamenBeta-Carotene + Vitamin E 

Beta-carotene 7 mg DL-α -Tocopherol acetate 25 mg; Softgels, orange, 2 oval, 
Prophylactic appliance in stress exposure and in supplementation of poor green and yellow fruits and vegetable diet especially in winter and in environment polluted area. Skin, hair and nail health state and good looking improvement
CLA(Conjugated Linoleic Acid)

 
CLA 80% 1000mg; Softgels, natural, transparent, 22 oblong, 
Conjugated Linoleic Acid (CLA) is a natural polyunsaturated fatty acid found in many wholesome foods. The human body cannot produce CLA. It is a powerful body fat burner. It also improves insulin sensitivity, inhibits the growth of prostate cancer, helps prevent the initiation, promotion and metastasis of breast cancer. CLA has an immune-enhancing effects as well as Anti-Atherogenic effects. Furthermore it lowers cholesterol and triglycerides, helps keep arteries clean.
Cod Liver Oil

 
Cod liver oil 500mg; Softgels, natural, transparent, 10 oval, 
Cod liver oil contains Vitamin A and D, EPA and DHA omega 3 fatty acids, which are converted in the body to produce prostaglandin that affect a wide variety of physiological processes due to their modulating effect on the action of hormones. The drug improves blood flow, reduces blood pressure, reduce risk of Coronary Heart Disease by reducing the likelihood of blood clotting, makes the heart less prone to arrhythmias. It alters the balance of blood fats in a favourable way and reduces the viscosity of blood, thereby facilitating blood flow. It affects bones and teeth, vision, skin and mucous membranes. It also helps in rheumatoid arthritis.
Coenzyme Q10 10mg

 
Coenzyme Q10 10 mg; Softgels, black, 3 oval, 
Owing to its anti oxidant properties coenzyme Q10 traps free radicals. Applied in heart diseases and overweight problems. Its action regulates arterial blood pressure and metabolism, prevents atheromatic circulatory system diseases, improves action of immune system.
Coenzyme Q10 30mgCoenzyme Q10 30 mg; Softgels, black, 5 oval, 
Owing to its anti oxidant properties coenzyme Q10 traps free radicals. Applied in heart diseases and overweight problems. Its action regulates arterial blood pressure and metabolism, prevents atheromatic circulatory system diseases, improves action of immune system.
Evening Primrose Oil

 
Evening primrose oil 500 mg; Softgels, natural, transparent, 10 oval, 
Applied in skin disorders and rash, has beneficent impact on heart and blood vessels, keeping stabilised cholesterol level. Improves overall condition before and during menstruation and also contributes to maintenance of proper functioning of joints.
Evening Primrose Oil + Vitamin E

 
Evening primrose oil 500 mg Vitamin +E 70 i.u; Softgels, natural, transparent, 14 oblong, 
In this combination natural form of vitamin E additionally protects the linoleic and gamma linoleic acids against oxidation damage.
Fish Oil


Fish oil 1000 mg; Softgels, natural, transparent, 20 oblong, 
Owing to the content of unsaturated fatty acids, regulates many significant functions in cells, reduces cholesterol level and triglycerides in arteries, prevents form heart attack and arteriosclerosis.
Garlic Oil

 
Garlic oil 2 mg; Softgels, natural, transparent, 4 oval, 
Preparation, having positive influence on alimentary tract, stimulates digestive glands increasing secretion of digestive juices. Widens blood vessels, reduces blood pressure, regulates heart rate. Additionally acts as antiseptic agent, builds up resistance against infections and deactivates carcinogenic substances, preventing from tumours.
Gingko Biloba Extract


Gingko Biloba 24% / 8% Extract 40mg; Softgels, green, 7,5 oval, 
Gingko biloba has beneficial effects on the circulatory system. It helps in treatment of short-term memory loss, headache, tinnitus (ringing in the ears) and depression by improving blood flow in the arteries and capillaries. Gingko Biloba relieve congestive symptoms of PMS, provides relief for asthma, allergy symptoms and chronic hepatitis. It is a powerful antioxidant and contributes to the oxidation of free radicals which are believed to contribute to premature aging and dementia. It protects the eyes, cardiovascular system and central nervous system.
Ginkgo + Crataegus + Passion Flower ExtractGinkgo Biloba Dry Extract 40 mg Crataegus Dry Extract 80 mg Passion Flower Dry Extract 20 mg; Softgels, red, 5 oval, 
Acts as tonic and sedative agent, favourises cerebral circulation improving cells oxygenation and nutrition. Applied as adjuvant in ischemic cerebral disorders, depressed memorization and concentration, vertigo, ear buzzing, irritability, anxiety. Administration especially indicated in elderly patients with atheromatic disorders.
Horse Chestnut Extract + Troxerutin

 
Horse Chestnut Dry Extract 100 g Troxerutin 200 mg; Softgels, light brown, 14 oblong, 
Favourises veinal circulation, preventing venostasis. Acts as anti exudative and anti oedematic agent. Applied in the treatment of veinal and lymphatic circulation disorders, in post-thrombotic syndrom, veinal thrombosis, varicose veins of low extremities and of hemorrhoids. Administered as adjuvant in the treatment of chronic veinal insulfficiency accompanied by exudations and oedemas.
Lecithin 1200mgLecithin 1200 mg; Softgels, natural, transparent, 22 oblong, 
Applied as adjuvant in depressed concentration and memorization, irritability, physical and nervous exhaustion, in convalescence and lipid metabolism disorders.
Lecithin 300mgLecithin 300 mg; Softgels, natural, 5 oval, 
Applied as adjuvant in depressed concentration and memorization, irritability, physical and nervous exhaustion, in convalescence and lipid metabolism disorders.
Loratadinum
Loratadinum 10mg; Softgels, blue, 5 oval, 

Drug alleviates allergic symptoms of upper airways and skin. It is also administered in allergic rhinitis (seasonal and continuous), nasal mucosa oedema, rhinorrhoea, sneezing, itching and burning sensation of eyes, prolonged idiopatic nettle rash. It becomes effective after approximately 30 minutes of administration and is active for about 24 hours.


Magnesium + Vit. E + Vit. B6DL-α-Tocopherol acetate 400 mg Pyridoxine Hydrochloride 10 mg Magnesium Oxid 150,8mg; Softgels, orange, 10 oval, 
Applied in magnesium, vitamin E and vitamin B6 deficiency prophylactics, administered in neurosis, increased stress susceptibility and chronic tiredness. Used as adjuvant in atheromatosis and hypertension therapy.
Pumpkin Seed OilPumpkin seed oil 500mg; Softgels, orange, 10 oval, 
Pumpkin seed oil is rich in oleic and linoleic acids. The oil contains anti-inflammatory properties effective in treating irritated bladder conditions and urination problems associated with benign prostatic hyperplasia stages 1 and 2. Pumpkin seed oil will relieve the symptoms associated with an enlarged prostrate. Pumpkin seed is a source of B-vitamins, essential fatty acids, protein and zinc.
Senna Leaf + Buckthorn Bark Extract

 
Senna Leaf Extract 25mg Buckthorn Bark Extract 67mg; Softgels, deep-red, 3 oval, 
Drug showing purgative action and having influence on motorial activity of colon. It is applied in constipation. It does not cause irritations of other parts of alimentary canal and becomes effective after 8-12 hours.
Serenoa Repens ExtractSerenoa Repens Extract 160 mg; Softgels, green, 3 oval, 
Owing to its anti androgenic and anti oedematic action this preparation is applied in the treatment of unitary disorders accompanying the benign prostatic hyperplasia, relieving such symptoms as pollakiuria, nycturia, depressed urine flowmetry, urostasis and pains caused by hyperplastic gland pression.
St. John's Wort ExtractSt. John's Wort Extract 150 mg; Softgels, brown, 5 oval, 
Drug showing soft anti depressive action, administered in mood depression, discouragement, apathy and menopausal psychological problems. Improves mood, psychosomatic activity and restores willingness to work.


Valerian Root + Passionflower + Hop Strobile Extract
Valerian Root Extract 60mg Hop Strobile Extract 40mg Passionflower Extract 40mg; Softgels, grey-green, 5 oval, 

Drug showing purgative action and having influence on motorial activity of colon. It is applied in constipation. It does not cause irritations of other parts of alimentary canal and becomes effective after 8-12 hours.
 
Vitamin A 12000 i.u.
Retinol palmitate 12 000 i.u.; Softgels, red, 2 oval, 

Treatment of vitamin A deficiency and as adjuvant in various skin diseases like acne, ichtyosis, psoriasis etc.

Vitamin A+E
Retinol palmitate 12 000 or 30 000 i.u + Tocopherol acetate 70 mg; Softgels, natural, 2 oval, 

Applied as adjuvant in geriatrics, ophthalmology (xerophtalmia, twilight blindness), atheromatosis, masculine sexual glands secretion disorders, menopausal disorders, epithelial keratosis.

Vitamin C
Acidum ascorbicum 200mg; Softgels, orange, 7,5 oval, 

Vitamin C (Ascorbic Acid) is a water-soluble vitamin and powerful antioxidant. It is needed to make collagen for muscles and blood vessels. It is important for wound healing and acts as a natural antihistamine. It helps in the formation of liver bile and helps the body to fight viruses.

Vitamin E natural 100 u.i.
D-αTocopherol acetate 100 u.i. ; Softgels, natural, transparent, 5 oval, 

Natural Vitamin E is a powerful antioxidant which protects cell membranes and other fat-soluble parts of the body. Studies suggest that supplementing with Vitamin E helps to prevent heart disease. Vitamin E appears to be the most effective supplement for slowing the progression of Alzheimer's Disease.

Vitamin E natural 400 u.i.
D-α Tocopherol acetate 400 u.i. ; Softgels, natural, transparent, 10 oval, 

Natural Vitamin E is a powerful antioxidant which protects cell membranes and other fat-soluble parts of the body. Studies suggest that supplementing with Vitamin E helps to prevent heart disease. Vitamin E appears to be the most effective supplement for slowing the progression of Alzheimer's Disease.

Vitamin E synthetic 100mg
DL-α Tocopherol acetate 100 mg; Softgels, light red, 2 oval, 

Prophylactic appliance in vitamin E deficiency and supplementation of vitamin deficits.

Vitamin E synthetic 400mg
DL-α Tocopherol acetate 400 mg; Softgels, natural, 7,5 oval, 
Drug applied in vitamin E deficiency treatment. Its action reduces the risk of atheromatic circulatory system diseases development. As antioxidant, vitamin E, facilitates free radicals elimination, decreasing their noxious effects. Favourises the immune system function and prevents the noeplastic diseases.


Vitaminum A 2500 i.u.
Retinol palmitate 2 500 i.u.; Softgels, light green, 2 oval, 

Prophylactic appliance in prevention of vitamin A deficiency.

Wheat Germ Oil
Wheat germ oil 1000mg; Softgels, natural, transparent, 16 oblong, 

Wheat germ oil is drawn from the heart of the finest wheat embryo by a refined cold pressing process. This process assures you that these capsules yield the essence of the golden wheat germ in its unrefined, undiluted state. The germ of wheat is the very life of the seed and a rich source of vitamin E, B Complex, plus protein factors. It protects the skin against free radicals and has a powerful antioxidant effect.





KDE-300 Automatic Soft Gelatine Encapsulation Machine

kde-300.gif (21411 bytes)kde-300-1.gif (7051 bytes)
Kwang Dah has established in 1955 and has been dealing with production of Capsule and Pharmaceutical machine for the past more than 50 years. During the early stage, We have made hard capsule and whole plant for hard capsule and soft gelatin capsule. In 1971, we have manufactured Semi-automatic Capsule Filling Machine, Automafic capsule filling machine, Blister Packing Machine for capsule and tablet, Counting Machine for capsule and tablet, high speed Automatic Strip Packing Machine for capsule and tablet ...etc. And, we have the ability to develop new products that will meet customer specific request. In fact, we are specialist and experience for producfion of capsules and capsule's series of machine, which is seldom seen in the world.
Manufacturing process


FEATURES:
KDE-300 Fully Automatic Soft Gelatin Encapsulation Machine is the most popular Soft Gelatin Capsule making machine in the world; and more than 90% of soft gelatin capsules in the world are produced by this kind of machine, which had been modified by QUI technics and experiences to the KDE-300. The features of fhe machine are:
1.
All parts and components in contact with gelatin ribbon and medieal solutions are made stainless steel or chrome plating thus meeting G.M.P. requirement.
2.
Gelatin ribbon making and filling with sealing operation can be completed on the same machine.
3.
Step/ess control for encapsulation machine.
4.
Easy for operation.
5.
Simple construction for maintenance easilv.

Produce Procedure :

The overall soft gelatin capsule process starts from the gelatin that is melted and de-bubbles via the gelatin tank, then mixing formula and color. Through the encapsulation machine, the melted gelatin solidify to the gelatin ribbon which the medical solutions are filled and sealed; then cutfing,formed into soft gelatin capsules. The soft gelatin capsules send to tumbler dryer via conveyor for shaping. After that, carry to fhe drying room for complete drying. Finally, soft gelatin capsules can be inspected and packed after the oily stains are removed from surface through the cleaning machine.


Applicability :

Apply to filling all substances which can not be melted in the water. They are ideal for encapsulation of a multitude of products, including Vitamins, Herb's, Drugs, Cosmetics, Lubricants and adhesives.


OBLONG
 

NO.
3
4
5
6
8
11
14
16
20
22
MINIMS
2.3-3.0
3.0-4.0
4.0-5.0
5.0-6.0
6.5-8.0
8.5-11.0
12.5-14.0
14.0-16.0
16.0-20.0
18.0-22.0
CC
0.142-0.185
0.185-0.246
0.246-0.308
0.308-0.370
0.400-0.493
0.524-0.678
0.770-0.862
0.862-0.986
0.986-1,232
1.109-1.355

OVAL
 

NO.
2
3
4
5
6
7 1/2
10
12
16
20
MINIMS
1.5-1.8
2.4-3.0
3.1-4.0
4.3-5.0
5.2-6.0
6.2-7.5
17.5-10.0
8.3-12.0
12.4-16.0
17.0-20.0
CC
0.092-0.111
0.148-0.185
0.191-0.246
0.265-0.308
0.320-0.370
0.382-0.462
0.462-0.616
0.511-0.739
0.764-0.986
1.047-1.232


ROUND
 

NO.
2
3
4
5
6
7
9
28
40
50
MINIMS
1.2-2.0
2.2-3.0
2.8-4.0
3.2-5.0
4.6-6.0
5.0-7.0
7.0-9.0
22.0-30.0
32.0-41.0
30.0-50.0
CC
0.074-0.124
0.136-0.185
0.172-0.246
0.197-0.308
0.320-0.370
0.308-0.431
0.431-0.554
1.355-1.848
1.9712.526
1.860-3.080

KDE-300 SOFT GELATINE ENCAPSULATION


Capacity
Item
PRODUCTION RATE/ HOUR
ROUND 3
45,200
ROUND 6
37,500
OBLONG 3
32,500
OBLONG 5
32,500
OBLONG 10
23,000
OBLONG 14
18,280
OVAL 3
32,760
OVAL 5
32,760
OVAL 10
23,760

Other Products 
1.
Automatic Capsule Filling M/C.
2.
Semi-automatic Capsule Filling M/C.
3.
Automatic Blister Pack M/C.
4.
Automatic Count M/C.
5.
Bath Counter.
6.
Automatic Strip Pack M/C.
7.
Cylindric Desiccant.
Capsule Filling Machine Series




No. 70, Gengzhou Rd, Wugu Dist, New Taipei City, 24874 Taiwan R.O.C.
TEL:886-2-2971-3333,886-2-29818888       FAX:886-2-2982-6645

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